Artigos / Articles

Chiocchetti,GM, Lopes-Aguiar, L, Miyaguti,NA, Lais Rosa Viana,LR, Salgado, CM1, Orvoën,OO, Derly Florindo,D Santos,RW and Gomes-Marcondes, MCC A Time-Course Comparison of Skeletal Muscle Metabolomic Alterations in Walker-256 Tumour-Bearing Rats at Different Stages of Life. 2021 Jun; 11(6): 404-422

Oliveira MMS, Salgado CM, Viana LR, Gomes-Marcondes MCC. Pregnancy and Cancer: Cellular Biology and Mechanisms Affecting the Placenta. Cancers (Basel). 2021 Apr 1;13(7):1667. doi: 10.3390/cancers13071667.

Oliveira SCP, Miyaguti NADS, Russell ST, Tobar N, Geraldo MV, Gomes-Marcondes MCC. Fish Oil Diet during Pre-mating, Gestation, and Lactation in Adult Offspring Rats on Cancer Cachexia Prevention. Mol Nutr Food Res. 2021 Mar 2:e2000863. doi: 10.1002/mnfr.202000863

Cruz B, Oliveira A, Viana LR, Lopes-Aguiar L, Canevarolo R, Colombera MC, Valentim RR, Garcia-Fóssa F, de Sousa LM, Castelucci BG, Consonni SR, Martins-de-Souza D, de Jesus MB, Russell ST, Gomes-Mardondes MCC. Leucine-Rich Diet Modulates the Metabolomic and Proteomic Profile of Skeletal Muscle during Cancer Cachexia. Cancers (Basel). 2020 Jul 13;12(7):1880. doi: 10.3390/cancers12071880.

Miyaguti NADS, Oliveira SCP, Gomes-Marcondes MCC.Maternal Leucine-Rich Diet Minimises Muscle Mass Loss in Tumour-bearing Adult Rat Offspring by Improving the Balance of Muscle Protein Synthesis and Degradation.Biomolecules. 2019 Jun 13;9(6). pii: E229. doi: 10.3390/biom9060229.

Cruz B, Oliveira A, Ventrucci G, Gomes-Marcondes MCC A leucine-rich diet modulates the mTOR cell signalling pathway in the gastrocnemius muscle under different Walker-256 tumour growth conditions. BMC Cancer. 2019 Apr 11;19(1):349. doi: 10.1186/s12885-019-5448-0.

Favero-Santos BC, Gomes-Marcondes MCC.Leucine can modulate the expression of proteins related to protein degradation signalling under mTOR inhibition in C2C12 cells.Cell Mol Biol (Noisy-le-grand). 2018 Jul 30;64(10):73-78.

Miyaguti NADS, de Oliveira SCP, Gomes-Marcondes MCC.Maternal nutritional supplementation with fish oil and/or leucine improves hepatic function and antioxidant defenses, and minimizes cachexia indexes in Walker-256 tumor-bearing rats offspring.Nutr Res. 2018 Mar;51:29-39. doi: 10.1016/j.nutres.2017.12.003. Epub 2017 Dec 28.

Cruz B, Oliveira A, Gomes-Marcondes MCC.L-leucine dietary supplementation modulates muscle protein degradation and increases pro-inflammatory cytokines in tumour-bearing rats.Cytokine. 2017 Aug;96:253-260. doi: 10.1016/j.cyto.2017.04.019. Epub 2017 May 8.

Viana LR, Canevarolo R, Luiz AC, Soares RF, Lubaczeuski C, Zeri AC, Gomes-Marcondes MC.Leucine-rich diet alters the 1H-NMR based metabolomic profile without changing the Walker-256 tumour mass in rats.BMC Cancer. 2016 Oct 3;16(1):764.

Cruz BL, da Silva PC, Tomasin R, Oliveira AG, Viana LR, Salomao EM, Gomes-Marcondes MC.Dietary leucine supplementation minimises tumour-induced damage in placental tissues of pregnant, tumour-bearing rats.BMC Cancer. 2016 Feb 4;16:58. doi: 10.1186/s12885-016-2103-x.

Viana LR, Gomes-Marcondes MC.A leucine-rich diet modulates the tumor-induced down-regulation of the MAPK/ERK and PI3K/Akt/mTOR signaling pathways and maintains the expression of the ubiquitin-proteasome pathway in the placental tissue of NMRI mice.Biol Reprod. 2015 Feb;92(2):49. doi: 10.1095/biolreprod.114.123307. Epub 2014 Nov 13